Related JetBlue to increase number of Caribbean fl

first_img RelatedJetBlue to increase number of Caribbean flights from BostonUS carrier JetBlue Airways will increase its number of flights to the Caribbean from Boston by 25 percent next summer.JetBlue increases flights from SFOUS carrier JetBlue Airways is increasing the number of flights to Boston’s Logan International Airport.JetBlue announces new flight between Orlando and San JoseAmerican low-cost airline JetBlue has announced that it will launch a new flight between Orlando and San Jose in Costa Rica. American low fares airline JetBlue has announced its intention to increase the number of flights it operates from Logan International Airport during 2009.The carrier will offer business and leisure passengers the opportunity to fly to a further 12 destinations in the US and the Caribbean from Boston, with it currently offering flights to 31 cities in seven different countries.Commenting on the proposed expansion, Marty St George, JetBlue’s vice-president of planning, said that it would benefit business people and those looking for a break.”With our expanded schedule, easy, same-day trips between Boston and the nation’s top business centres like Charlotte and Raleigh are now a breeze,” he said.”And when you’re ready for a break, our new year-round flights to places like St. Maarten and San Juan make getting away even easier.”JetBlue will re-introduce its route between Boston and San Francisco International Airport on May 1st, while also increasing its frequency of flights to a number of cities including Chicago and Pittsburgh.The New York based airline was the first carrier in the US to introduce free in-flight email and instant messaging services to its passengers. ReturnOne wayMulti-cityFromAdd nearby airports ToAdd nearby airportsDepart14/08/2019Return21/08/2019Cabin Class & Travellers1 adult, EconomyDirect flights onlySearch flights Maplast_img read more

DTG Testing the test house subsidiary of the Digi

first_imgDTG Testing, the test house subsidiary of the Digital TV Group, and test and measurement specialist Mirifice, have extended their existing partnership to include automated MHEG testing of set-top boxes, recorders and iDTVs.DTG Testing and Mirifice have developed an automation system for MHEG based on Mirifice’s MiriATE product. The system automates approximately 80% of the core MHEG tests.DTG Testing has also released an MHEG automated test suite for manufacturers to purchase for pre-compliance testing, prior to submission to DTG Testing for final testing.“DTG Testing is committed to continually enhancing the service we offer to manufacturers.” said Richard Carlton, associate director, DTG Testing. “The introduction of MHEG automation will reduce the time taken to test products and provide a more controlled testing environment, ensuring even greater consistency of test results.”DTG Testing introduced Mirifice’s MiriATE automation system into its testing processes in 2009 in order to align with the requirements of UKAS ISO /IEC 17025. The system is able to automatically interpret a receiver’s video and audio output, while controlling the device inputs and environment and is capable of testing up to 96 receivers in parallel 24 hours a day.DTG Testing said it plans to introduce automation throughout its range of manual test suites in the near future.last_img read more

YouViews number one priority is to achieve scale

first_imgYouView’s number one priority is to achieve scale, according to Richard Halton, CEO of the UK connected TV platform.“It has to be a platform of scale, but our shareholders are in this for the long haul,” he told IBC attendees this morning. Halton said the lack of penetration so far for Google TV and Apple TV meant that YouView had “not missed the boat”. He pointed out that it was the first online TV platform to be chosen by Now TV from BSkyB and Channel 5’s Milkshake. Halton said that further content news would be announced over the remaining months of the year.YouView has had a “good start”, with positive reviews and a good and expanding range of content. Halton said that the next phase would be to begin marketing the service in earnest. The platform would develop, and the next functional release of the YouView software is ready to deploy, said Halton. He said apps for companion devices would be developed in tandem with the core platform.Having key brands in one place, and the integration of the linear and on-demand service was hard to do and gave YouView an advantage over other connected TV platforms and media streamers, said Halton.Halton said that YouView’s shareholders had a range of priorities and it was important to meet their individual needs. He said the platform, in addition to benefiting the free-to-air broadcasters, offered possibilities for a wide range of new revenue streams, including targeted advertising and new pay revenues.“For the ISPs, YouView is strategically their TV platform,” said Halton. TalkTalk had already announced its proposition, making YouView boxes available for free to top-tier customers.YouView will offer instant access to about £3 billion (€3.8 billion) worth of content every year through one simple interface thanks to its backwards-in-time capability, said Halton. “For 70% of Freeview homes in the UK, pause and rewind of live TV is new,” he said. Most users did not have Freeview Plus boxes. He said this functionality would feature significantly in YouView’s marketing campaigns.Halton said that YouView was now stocked in 800 stores in the UK and both Humax and Huawei had YouView boxes on display at IBC.last_img read more

Emiliano Calemzuk Former Fox and Shine boss Emilia

first_imgEmiliano CalemzukFormer Fox and Shine boss Emiliano Calemzuk has created a new content company, Rampante, and teamed up with publishing group Time Inc. to form a new production company.The new prodco will make video content for a new multiplatform library and will also help Time distribute its video content.Time Inc. brands include Sports Illustrated, Entertainment Weekly, Food & Wine and Fortune. The Time Inc.-Rampante content will be based around Time brands and it will be distributed to linear channels and SVOD and digital platforms in the US and internationally, Joe Ripp, Time CEO said.“We are expanding our video strategy to leverage the breadth of our portfolio in a cohesive, high-volume way,” said Ripp. “By partnering with Emiliano, we are gaining experience in television production and international channel distribution. Moreover, without taking on unnecessary overhead, we will have an immediate presence in Los Angeles.”Calemzuk said: “After spending time with executives and editors, I am convinced that the strength and depth of the Time Inc. portfolio has the potential to lead the long-form digital video world in the decades to come.”He added: “I also look forward to assisting Time Inc.’s management in developing strategies to evolve the subscription model for the next generation of consumers.”Calemzuk was boss of Shine America until early 2012. Upon his departure, Shine said he was taking a “break from day-to-day executive duties”. With that break now over, he has formed Rampante (Spanish for ‘rampant’).Prior to Shine, Calemzuk served a twelve-year stint at News Corp. (now 21st Century Fox), where he ran cable programming arm FtvS and before that, international channels division, Fox International Channels.West Coast-based Rampante is described as a “next-generation content production and distribution company focused on high-growth segments of the media business”. It will work in digital and regular TV production in the US, US Hispanic and international TV markets.last_img read more

In This Issue Euro falls with job losses in Spai

first_imgIn This Issue.*Euro falls with job losses in Spain… *US data is mixed… *Elections won’t have an impact on the $… *NZD trade deficit widens, forcing the kiwi lower…And, Now, Today’s Pfennig For Your Thoughts!The US Dollar gains ground as European unemployment rises…Good day. TGIF! As Chuck indicated yesterday morning, he has to report to a classroom today for some continuing education and has therefore left the reins of the Pfennig in my hands. I gladly take them and will try to steer us through the economic factors which are driving the markets.  As I turn the screens on this morning, the dollar has spiked up with the dollar index jumping back up to levels we haven’t seen in over a month. The euro is the main driver of the dollar index, so it is no surprise that the euro is down this morning. The euro is dropping after a report was released showing Spain’s jobless rate rose to 25.02% from 24.6% in the previous quarter.  This was the highest jobless rate in Spain in over 35 years and increased investors’ concerns.  Other reports showed French household sentiment dropped for a fourth month and euro-area services and manufacturing output contracted.  The data certainly illustrate just how tough times are in the European economy, and investors have started pushing the euro back below $1.30.It actually amazes me that the euro has been as resilient as it has.  Spain is all but certain to have to ask for a bailout, and both Greece and Italy continue to struggle. Even the French economy is in bad shape.  French President Francois Hollande had pledged to overhaul the French economy when he took office 6 months ago.  But recently the French president has been downplaying these promises.  Hollande pledged to get deficits below 3 percent of gross domestic product in 2013, but that looks unlikely as the IMF expects the French economy will only grow at a .4% rate next year and the deficits remain.But investors seem to be comfortable with the fact that the European countries are going to take longer to recover. Even recent news that Greece is going to need another 2 years to meet their budget targets doesn’t seem to have bothered investors in the euro. I guess when you compare Europe with the US it really doesn’t look all that bad.We will get a better view of the US economy with the release of 3rd quarter GDP.  Gross Domestic Product is predicted to have increased 1.8% during the past quarter after rising 1.3% in the previous quarter.  While it is moving in the right direction, this would be the first time GDP was below 2% in consecutive quarters since the US economy emerged from recession in 2009.  Another report is predicted to show confidence declined slightly as the U of Mich. Confidence is projected to fall slightly. Yesterday’s weekly jobs report showed a decrease in initial jobless claims to 369K from an adjusted 392K last week.  Continuing claims remain at worryingly high levels at over 3,254,000 out of work. Another report had better news as Durable Goods orders increased 9.9% in September after a dramatic 13.1% drop in the previous month.  And finally, a report showed pending home sales dropped to just .3% during September compared to a drop of 2.6% during August. The YOY number was better, showing an increase of 8.5% which indicates the US housing market is still improving, albeit slower than many expected.As all of you know, Mike Meyer has been off the desk the past couple of weeks enjoying his honeymoon with his new bride.  With Mike gone I’ve had the pleasure of taking a few more calls than typical, and I have to say I enjoy getting back on the phones to speak with the great World Markets clients.  One of the most common questions we have been fielding lately is ‘who do you think is going to win the election’ and the automatic follow up of ‘and what will the election mean for the dollar”? I’m smart enough not to try to predict the election (it is hard enough trying to figure out where the currencies are going over the next few years!); but I do let our clients know that the elections probably won’t have too much of an impact on the direction of the dollar in the next few years.  The dollar is headed lower, and there isn’t much either party can do about it.  I know this may upset readers on either side of the political divide, as they believe their ‘man’ has the stuff to lead our country in the right direction.  But the massive amounts of debt which we have accumulated are not going to magically disappear on November 7th, and this debt is what will continue to drive the value of the dollar lower. A story which appeared in the Journal of Accountancy yesterday partially confirmed my thoughts on the election. (No, I don’t typically peruse the Journal of Accountancy, but I do get a summary of the day’s top financial stories sent to me by the CFA organization and spotted it there). The article quoted a survey which was conducted at the Association for Financial Professionals.  In the survey, 63% of executives said that the outcome of the US Presidential election won’t have a significant effect on business conditions. Unfortunately our path is already set, and it won’t be immediately impacted by the election, whether we get a change at the top or not.  That is not to say we shouldn’t vote, nor that a change in the direction of the economy is not possible.  Just that we won’t see any immediate impacts, change will take time to work its way through the economy.No, the results of the election won’t determine the short term course of the dollar, but just getting past November 6th probably will.  You see markets don’t like uncertainty, and with the election basically a toss-up many investors are not wanting to commit funds to the markets.  So the results of the election probably have less to do with the direction of the markets than just getting past them.  I know I am certainly looking forward to an end of all of the political ads!And don’t forget about that fiscal cliff which is still waiting for us at year end.  The election won’t make that go away either.  Another story I read stated that nearly 1 million jobs have already been lost due to the fiscal cliff.  The story, which appeared in the Washington Post pointed to a study by the National Association of Manufacturers which says employers are laying off workers and leaving vacant positions empty as they worry about what will happen if / when tax hikes and spending cuts take effect January 1st.  The study concluded that nearly 6 million jobs will disappear through 2014 and the jobless rate will rise close to 12% if the country is pushed off this cliff.  Scary stuff, but that is exactly what was intended.  The ‘fiscal cliff’ was instituted in order to force the hand of congress and our administration; making them make the very tough decisions which are necessary in order to push our economy toward a more sustainable path.  Perhaps the cliff is exactly the ‘tough love’ our economy needs, but the markets certainly don’t think we will be forced over it. The next two months will certainly be interesting. As Chuck reported, the RBNZ left rates unchanged yesterday and the kiwi moved higher.  But a report released overnight has the New Zealand dollar moving lower.  New Zealand’s trade deficit expanded to the widest level since 2009 as exports fell and a stronger kiwi encouraged imports.  The NZ$888 million deficit was actually a bit lower than expected.  Dairy exports, which make up nearly one quarter of annual exports in NZ, dropped 12 percent.  Central bank Governor Graeme Wheeler blamed the higher kiwi for ‘undermining export earnings’ and encouraging imports.  This is not a good sign for clients holding kiwi, as the new head of the RBNZ continues to indicate he would like to see a weaker currency. The Australian dollar also fell overnight as investors worried about demand in Asia.Then There Was This. A report by Schroder Investment Management, Ltd. dated October 23 suggests global economic growth may be reaching a saturation point.  The concept implies global demographic and climate changes, combined with an expanding consumption in emerging markets will limit global growth.  According to the story, ‘Forecasts show that by 2050, the world’s population will climb by 2 billion, or 30 percent, and 3 billion people with the ability to spend $10 to $100 a day will join the consumer market.’ World gross domestic product could jump threefold according to the report.While this would seem to be positive news, the report points out that this growth will push the global environment to its limits.  “Investors need to recognize that pressure will build for regulations more suited to resource scarcity, such as punitive taxes on companies that use environmental assets excessively.”  The report calls into question the sustainability of global growth as demand for resources dramatically increases.While the report has some scary conclusions, the news that global growth is going to increase is certainly positive and meshes with what we are expecting to see.  Commodities are going to be at an even greater premium in the coming years, and the countries who export commodities should continue to see good demand for their currencies.To recap. The euro fell overnight after Spanish unemployment increased to over 25%.  US data released today is expected to show GDP increased to 1.8% from 1.3% last quarter. The US elections are looming, but the election won’t have any impact on the dollar as the debts and deficits will remain in near term.  The NZD trade deficit widened and New Zeland’s central bank head blames the high price of the kiwi for the increase in imports. Currencies today 10/26/12. American Style: A$ $1.0325, kiwi .8187, C$ $1.003, euro 1.2894, sterling 1.6105, Swiss $1.0662. European Style: rand 8.7574, krone 5.7970, SEK 6.7325, forint 219.85, zloty 3.2184, koruna 19.3435, RUB 31.504, yen 79.80, sing 1.2233, HKD 7.7503, INR 53.575, China 6.2494, pesos 13.0745, BRL 2.0265, Dollar Index 80.228, Oil $85.55, 10-year 1.77%, Silver $31.6975 and Gold. $1,703.45That’s it for today. I spent a chilly night in the stands with my wife and daughter as we watched Brendan’s football team win their first playoff game.  Now they get to move on to the second round and face a tough opponent on Halloween night.  Mizzou’s homecoming is this weekend, and my Aunt Marilyn is flying in from Texas to attend the football game with my mom. I look forward to spending some time with my aunt, who is a real hoot and has a special attachment to MIZZOU; during her college days she was the school’s mascot, Truman the Tiger.  Hopefully Mizzou will be able to win for their big homecoming crowd.  Congratulations to the SF Giants who head over to Detroit with a 2 game lead in the World Series.  I am running late as usual, so I will get this out the door.  I hope everyone has a Fantastic Friday and a Wonderful Weekend. Thanks for reading the Pfennig.Chris Gaffney, CFA Vice President EverBank World Markets 1-800-926-4922 1-314-647-3837last_img read more

If theres one thing were grateful for on Shots

first_imgIf there’s one thing we’re grateful for on Shots, it’s our passionate, engaged audience. Our stories often prompt a lively response from readers and people who hear us on the radio. This was definitely the case with Monday’s look at the use of permethrin-treated clothing to prevent tick bites, which can cause a lot of nasty diseases.Permethrin is a synthetic pesticide that’s similar to natural compounds found in chrysanthemums. When you spray permethrin on your clothes, a study published in May found, it incapacitates ticks quickly, rendering them unable to bite.It didn’t take long for emails to come flooding in. Most were from concerned cat owners.”Permethrin is very toxic to cats,” wrote Charles Fischer, who lives in Chapel Hill, N.C. “Suggesting that people spray their garments with permethrin to prevent tick bites without a cat disclaimer is very dangerous.”Others agreed. “NPR has always been a wonderful source of great information,” wrote Colleen Scott-Jackson of Jacksonville, N.C. “I would hate to see any cats harmed because an important piece of information is left out of the story.”We certainly didn’t want any cat catastrophes, so we decided to look into this a little further. Here’s what we found.Cats are more sensitive to permethrin than other mammals, but cat lovers can still use the insecticide as long they’re careful about it, veterinarians say.”It’s the dose that makes the poison,” says Dr. Charlotte Means, director of toxicology at the ASPCA Animal Poison Control Center.The biggest problem for cats is when they are exposed to highly concentrated permethrin products meant for use in dogs, she says. These products may be 45 percent permethrin or higher. “Some cats will be so sensitive that even just casual contact with a dog that’s been treated will be enough to cause clinical signs, including tremors, seizures and in the worst-case scenario — death,” she says.But the concentration of permethrin in household sprays is much, much lower – typically less than 1 percent. And with concentrations of 5 percent or less, Means says, there are rarely problems.”Of course you can always get an individual [cat] who is more sensitive, but for most animals there are going to be minimal clinical signs,” she says.There are some simple rules that can help minimize the risk.”Don’t put the dog product on the cat,” says Dr. Lisa Murphy, associate professor of toxicology at the University of Pennsylvania School of Veterinary Medicine. She agrees that the most dangerous scenario for cats is an accidental exposure to a highly concentrated product meant for dogs. “Cats seem to be deficient in one of the primary mechanisms for metabolizing permethrin,” she says, which is why they are more susceptible to the chemical. If an animal “isn’t able to normally metabolize it, break it down and excrete it, it can build up and be more likely to cause problems.”If you’re concerned your cat may have been exposed to permethrin, the most common symptoms are skin irritations — redness, itching and other signs of discomfort. “The animal may be frantic if they have something uncomfortable on their skin,” Murphy says. “They may be scratching, digging and rolling because it’s uncomfortable.”These skin reactions are usually easily treated by washing the affected area with mild, liquid dishwashing detergent. If the cat fights back, you can take it to the vet for a bath.Other reactions to watch for are drooling or pawing at the mouth. “Cats seem particularly sensitive to bad tastes in their mouths,” Murphy says. This can be helped by gently rinsing out the mouth, or offering the cat some water or milk to take away the bad taste.But if you see signs of neurological problems — tremors, twitching or shaking — it’s time to take the cat to the vet right away.Even then, if there aren’t any complications, “the prognosis for a full recovery is excellent,” Murphy says.”The way I look at it, as a veterinarian, is it’s all about making choices,” Murphy says. Ticks, fleas, lice and mosquitoes do carry lots of diseases that permethrin and other insecticides can help prevent, she says: “All sorts of things that we wouldn’t wish on ourselves or our pets.”So the bottom line when it comes to permethrin and tick-bite prevention is: If you have a cat, be extra careful.If you’re spraying your clothes, do it somewhere the cat doesn’t have access to. And let the clothes dry thoroughly before you and your cat reunite.”If you are spraying a 1 percent concentration on clothing and it dries, it’s unlikely that you’ll see any problems with the cat,” Means says. To be extra cautious, don’t leave permethrin-treated clothing near where your cat sleeps. And make sure to change clothes after you wear them outside, so the cat can jump in your lap without you having to worry, she says.And it may seem obvious, but if you’re using a permethrin soak for your clothes, make sure the cat doesn’t drink from the bucket.Finally, read the label for the permethrin product you’re using. Check the concentration and use only as instructed. And before treating any animal directly with any insecticide, check with your vet first. Copyright 2018 NPR. To see more, visit http://www.npr.org/.last_img read more

Belgians Are Hunting Books Instead of Pokémon

first_img This story originally appeared on Reuters Project Grow Register Now » Next Article Belgians Are Hunting Books Instead of Pokémon Free Webinar | July 31: Secrets to Running a Successful Family Business August 26, 2016 Image credit: Reuters | Kim Kyung-Hooncenter_img Add to Queue Reuters Inspired by the success of Pokémon Go, a Belgian primary school headmaster has developed an online game for people to search for books instead of cartoon monsters, attracting tens of thousands of players in weeks.While with Pokémon Go, players use a mobile device’s GPS and camera to track virtual creatures around town, Aveline Gregoire’s version is played through a Facebook group called “Chasseurs de livres” (“Book hunters”).Players post pictures and hints about where they have hidden a book and others go to hunt them down. Once someone has finished reading a book, they “release” it back into the wild.”While I was arranging my library, I realized I didn’t have enough space for all my books. Having played Pokémon Go with my kids, I had the idea of releasing the books into nature,” Gregoire told Reuters.Though it was only set up a few weeks ago, more than 40,000 people are already signed up to Gregoire’s Facebook group.The hidden tomes range from books for toddlers through to Stephen King horrors, placed around Belgian towns and countryside, often wrapped in clear plastic to keep off the rain.The Detournay family from the town of Baudour in southern Belgium said the game was now part of their morning walks. They found one book and left four others for people to find.”My daugther said it’s like hunting for easter eggs, only with books,” Jessica Detournay said.When they returned home, they received a Facebook notification informing them that somebody had already found two of their books.Gregoire is now contemplating taking the game a step further and creating an app for it.(By Maria Haase Coelho; Editing by Robert-Jan Bartunek and Robin Pomeroy) 2 min read Learn how to successfully navigate family business dynamics and build businesses that excel. –shareslast_img read more

Dods Group Plc Acquires Meritgroup Limited a B2B Data and Technology Specialist

first_imgDods Group Plc Acquires Meritgroup Limited, a B2B Data and Technology Specialist PRNewswire4 days agoJuly 22, 2019 Dods Group Plc, the leading business intelligence, media and events company, announced that it has acquired Meritgroup Limited, a specialist data engineering and technology provider to the B2B media and information sector, for £22.4 million.For 186 years, Dods Group has been providing its customers with business-critical information and access to key decision-makers within the policy, politics and public sector arenas. This information helps them navigate the complex and ever-changing landscapes of UK and EU public policy, in order to drive growth, mitigate risk and manage their corporate reputation.The Dods portfolio includes renowned business intelligence and reference data services, alongside iconic media channels and widely recognised events and training programmes.Marketing Technology News: Introducing Shutterstock Elements, Thousands of Cinema-Grade Video Effects for FilmmakersMerit powers some of the world’s leading B2B information services brands.  It has been at the forefront of exploring new technologies in the world of B2B data engineering for fifteen years, and has significant resident expertise and knowledge in data management.This acquisition will allow Dods Group to enhance and extend its products and services, and reflects its intention to become a significant augmented intelligence business; pioneering the use of a combination of machine learning, artificial intelligence and human application to inform actionable business outcomes.Simon Presswell, CEO of Dods Group, said: “Providing both actionable business intelligence and strategic engagement with senior decision-makers across the Policy and Civil Service spectrum throughout the UK and Europe has proven invaluable to our customers. It is this critical access and insight into our audiences that allows us to enhance our product portfolio in addressing new challenges our customers are facing.“Merit has been a long-standing partner and we are delighted to welcome them into an expanded business. We are both deeply embedded in our customer workflows with a shared focus on data. Merit’s data processing and automation capabilities complement Dods’ data and content creation and analytical competencies. This combination will enable us to bring a new generation of products and services to our customers, faster.”Marketing Technology News: GCOM Software Announces Ernie Connon as New Chief Growth OfficerCornelius Conlon, CEO of Merit, added: “Merit feeds many of the leading B2B intelligence products by enhancing product data. We have been developing more advanced technologies as we’re now helping our customers build Artificial Intelligence into their products.“As both businesses are looking to utilise machine learning in gaining efficiency and scale of data enhancement, and build better products and services for our customers, we believe that combining resources will accelerate our progress and we’re very excited by this opportunity.”The businesses will continue to operate under their current brands, endorsed by the parent company, Dods Group Plc.Marketing Technology News: Blackstone Announces Agreement to Acquire Vungle, a Leading Mobile Performance Marketing Platform b2b dataDods GroupMarketing Technology NewsNews Previous ArticleTellius and Snowflake Partner to Deliver Cloud-Native Augmented Analytics at ScaleNext ArticleAprimo Promotes Ed Breault to Chief Marketing Officerlast_img read more

Intense weight loss with the soups and shakes could reverse type 2

first_imgImage Credit: Bon Appetit By Dr. Ananya Mandal, MDMar 6 2019A new study looking at the long term effects of losing substantial amounts of weight has found that it could reverse type 2 diabetes in more than a third of the patients. With the rising epidemic of obesity and type 2 diabetes around the world, this could be an important finding. The participants of the study took a specifically low calorie diet comprising of just soups and shakes and a total of around 800 calories per day. They consequently lost substantial amount of body weight. In a third of the patients, this led to reversal of their type 2 diabetes and at the end of two years the patients remained in remission from their disease, the study called Direct found. The results of the study were published in the latest issue of the Lancet Diabetes & Endocrinology journal.According to researchers this study shows that type 2 diabetes need not be a lifelong condition. Co-primary investigator of the study, Prof Roy Taylor from Newcastle University explained that type 2 diabetes now can proven not to be an “inevitably progressive disease”. He said in a statement, “We now understand the biological nature of this reversible condition. However, everyone in remission needs to know that evidence to date tells us that your type 2 diabetes will return if you regain weight.”For the Direct study the team included 49 GP practices across Scotland and Tyneside. Around 300 people with type 2 diabetes and a body mass index between 27 and 45 Kg/ m2 were part of this study. The participants were divided into two groups – half received standard care while the other half received only low-calorie formula meals that was up to 800 calories per day for 12 to 13 weeks of the study. After the study period the group on low calorie diet had a nurse or a diet advisor to guide them back to a normal diet. This helped them maintain the lost weight.Related StoriesDiet and physical exercise do not reduce risk of gestational diabetesUranium toxicity might have caused obesity and diabetes in Kuwait, finds new studyMetformin use linked to lower risk of dementia in African Americans with type 2 diabetesResults showed that at the end of the first year of the study, 46 percent of the participants on the low calorie diet reversed their type 2 diabetes. After two years from the start of the study, 36 percent were in remission from their type 2 diabetes, the study found. Over 64 percent of the individuals who lost over 10kg of their body weight were still free of type 2 diabetes after two years after having shaken it off.It was expected that some participants would gain back some of the weight that they had lost. Some of them gained weight between the first and the second year. Participants who were in remission after one year however stayed in remission and had a more average weight loss (15.5 Kg) compared to those who did not achieve remission (12 kg on an average). Remission was defined as a persistent HbA1c levels of less than 48mmol/mol (6.5%) without the use of any anti-diabetic medication.Study leader, Prof Michael E J Lean, MD from Glasgow University in a statement said, “People with type 2 diabetes and healthcare professionals have told us their top research priority is: ‘Can the condition be reversed or cured?’ We can now say, with respect to reversal, that yes it can. Now we must focus on helping people maintain their weight loss and stay in remission for life.”While the NHS England is planning on following NHS Scotland that has started schemes of calorie restriction for type 2 diabetics, experts have warned that more studies are needed to ensure safety of such interventions. They have warned that calorie restriction is not suitable for all individuals and should be done only under medical supervision and with adequate support. Diabetes UK, the charity that financially supported this study said, “We know type-2 diabetes is a complex condition and this approach will not work for everyone.”center_img Source:https://www.thelancet.com/journals/landia/article/PIIS2213-8587(19)30068-3/fulltextlast_img read more

Inherited form of rickets improves more with new injectable medicine than conventional

first_imgReviewed by James Ives, M.Psych. (Editor)Mar 25 2019Burosumab, a new injectable medicine to treat X-linked hypophosphatemia (XLH), an inherited form of rickets, demonstrates superior improvements in rickets and other outcomes compared with conventional therapy in an international, phase 3 clinical trial in children. Results from what investigators called the first head-to-head study comparing the new drug with conventional treatment for this rare disease will be presented Sunday at ENDO 2019, the Endocrine Society’s annual meeting in New Orleans, La.”These improvements with burosumab have the potential to change the lives of children with XLH as they grow,” said study principal investigator Erik Imel, M.D., associate professor of medicine and pediatrics at Indiana University School of Medicine in Indianapolis, Ind.XLH affects about 3,000 children and 12,000 adults in the United States, the Food and Drug Administration (FDA) estimates. Typically, XLH causes rickets, bowed legs, bone pain and short stature.Related StoriesRevolutionary gene replacement surgery restores vision in patients with retinal degenerationResearch team receives federal grant to study obesity in children with spina bifidaNew therapeutic food boosts key growth-promoting gut microbes in malnourished childrenPeople with XLH have high levels of the hormone fibroblast growth factor 23, or FGF23, which causes low blood levels of phosphorus (hypophosphatemia). Conventional therapy has long been multiple daily doses of oral phosphate and active vitamin D (e.g. calcitriol), according to Imel.The study included 61 XLH-affected children ages 1 to 12 years who previously received conventional therapy with oral phosphate and active vitamin D but still had evidence of rickets on X-rays. Patients were randomly assigned to continue this conventional therapy or switch to receive burosumab injections given every two weeks. Radiologists who were unaware of participants’ drug assignments reviewed their X-rays and assigned a score for improvement of rickets.By 40 weeks of treatment, that improvement was more than two times greater for the burosumab group than the conventional therapy group, Imel noted. Substantial healing of rickets occurred in 72 percent of participants receiving burosumab (21 of 29), the researchers reported, versus only 6 percent in the conventional therapy group (two of 32). Burosumab also reportedly led to greater improvements in leg deformities, height and distance walked in a 6-minute test, as well as larger increases in serum phosphorus and active vitamin D levels.”We now know the magnitude of benefit from the new medication, burosumab, versus the prior approach with conventional therapy,” Imel said. “This information is critical for doctors making treatment decisions for their patients with XLH.”In April 2018, the FDA approved burosumab, which has the brand name Crysvita, for patients with XLH ages 1 year and older. Burosumab binds and inhibits FGF23, according to its manufacturer, Ultragenyx Pharmaceutical Inc., which funded the new study in partnership with Kyowa Kirin International of Japan. The study took place in the United States, Canada, the United Kingdom, Sweden, Australia, Japan and Korea.Source: http://www.endocrine.org/last_img read more

Study Consuming sugar does not improve mood and makes people more tired

first_img sugar consumption has virtually no effect on mood, regardless of how much sugar is consumed or whether people engage in demanding activities after taking it. people who consumed sugar felt more tired and less alert than those who had not. the idea of a ‘sugar rush’ is a myth without any truth behind it. Reviewed by James Ives, M.Psych. (Editor)Apr 5 2019Sugar does not improve mood and it can make people less alert and more tired after its consumption – according to a new study by the University of Warwick, Humboldt University of Berlin, and Lancaster University.The research team set out to examine the myth of the ‘sugar rush’: can sugar really put you in a better mood? Using data collected from 31 published studies involving almost 1300 adults, Dr Konstantinos Mantantzis at Humboldt University of Berlin, Dr Sandra Sünram-Lea at Lancaster University, and Dr Friederike Schlaghecken and Professor Elizabeth Maylor in the University of Warwick’s Department of Psychology investigated the effect of sugar on various aspects of mood, including anger, alertness, depression, and fatigue.Related StoriesScientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid researchSchwann cells capable of generating protective myelin over nerves finds researchOne pint of beer or large glass of wine can compromise person’s sense of agencyThey also considered how factors such as the quantity and type of sugar consumed might affect mood, and whether engaging in demanding mental and physical activities made any difference.The researchers found that : Professor Elizabeth Maylor, from the University of Warwick, commented:”We hope that our findings will go a long way to dispel the myth of the ‘sugar rush’ and inform public health policies to decrease sugar consumption.”Dr Konstantinos Mantantzis, from Humboldt University of Berlin, who led the study, said:”The idea that sugar can improve mood has been widely influential in popular culture, so much so that people all over the world consume sugary drinks to become more alert or combat fatigue.”Our findings very clearly indicate that such claims are not substantiated – if anything, sugar will probably make you feel worse.”Dr Sandra Sünram-Lea added:”The rise in obesity, diabetes and metabolic syndrome in recent years highlights the need for evidence-based dietary strategies to promote healthy lifestyle across the lifespan. Our findings indicate that sugary drinks or snacks do not provide a quick ‘fuel refill’ to make us feel more alert.”center_img Source:https://warwick.ac.uk/newsandevents/pressreleases/no_such_thinglast_img read more

Vitamin D is essential for preventing preeclampsia

first_imgReviewed by Alina Shrourou, B.Sc. (Editor)Jul 9 2019A new study suggests vitamin D may reverse impaired cell interactions in the blood vessels that occur in preeclampsia- a pregnancy complication characterized by high blood pressure. The finding is published ahead of print in the American Journal of Physiology- Cell Physiology.Preeclampsia can threaten the life and future health of both a pregnant person and their offspring. Damage to the maternal endothelium-;the lining of the blood vessels-;is a feature of the condition, reflected by a reduced number of specialized cells (endothelial progenitor cells, or EPCs) that circulate in the blood and help with the repair of the endothelium. Dysfunction of fetal umbilical vein endothelial cells and fetal EPCs may also occur in preeclamptic pregnancies. Umbilical vein endothelial cell samples-;taken immediately after delivery of the baby-;are often used to study the regulation of endothelial cell function.Related StoriesSunscreen benefits can be obtained without compromising vitamin D levelsVitamin D deficiency at birth increases risk of high blood pressure in childrenLow vitamin D associated with potentially harmful vaginal bacteria in pregnant black womenVitamin D plays a role in regulating the cardiovascular system. Previous studies have shown that low levels of vitamin D have been linked to the development of preeclampsia, which is classified as a cardiovascular disease. Researchers from Hannover Medical School in Germany and the University of Pittsburgh School of Medicine’s Magee-Womens Research Institute studied the effects of vitamin D on the interaction between EPCs and umbilical cord endothelial cells-;which facilitate endothelial repair-;in women with preeclampsia.They found the EPCs and umbilical vein cells did not integrate and communicate as well with each other as when they were exposed to endothelial cells from healthy pregnancies. However, when the EPCs and umbilical vein cells were treated with vitamin D, these impaired interactions were reversed. “We found a stimulating effect of vitamin D on cell-cell interactions that may be important for endothelial homeostasis and repair,” the researchers wrote.”Even though vitamin D deficiency is only one risk factor for [preeclampsia], sufficient vitamin D status at conception and throughout pregnancy might improve maternal and offspring vascular health in pregnancy and thereafter. Whether the observed cellular changes persist in the neonatal period and childhood and are a possible early marker of an increased cardiovascular risk of the progeny of [preeclamptic] pregnancies has to be investigated by further studies,” the researchers wrote. Source:American Physiological Society (APS)Journal reference:Brodowski, L. et al. (2019) The role of vitamin D in cell-cell interaction of fetal endothelial progenitor cells and umbilical cord endothelial cells in a preeclampsia-like model. American Journal of Physiology—Cell Physiology. doi.org/10.1152/ajpcell.00109.2019.last_img read more

Rosberg happy to see Hamilton break all records

first_imgIf Valtteri Bottas, Hamilton’s current team mate and battered title rival, wants any tips — not that Rosberg feels the Finn needs any help from him — then he can expect plenty of sacrifice and suffering.Rosberg revealed that he spent up to eight hours a week with a sports psychologist during that 2016 season, undergoing the mental equivalent of boot camp to beat the one man with the same machinery.”Two hours every second day of mental training. It was a huge process and just gave me so much and that’s one of the big reasons why I ended up being world champion,” said the German, who retired days after winning his title.Son of 1982 world champion Keke, Rosberg started working with the psychologist in 2007, after a debut season with Williams, but ramped it up significantly for that final campaign.”I just dedicated my whole every single breathing second of my life to winning that next race and becoming world champion,” he said.”Lewis drove me to go searching for ways to be better than I ever thought I could be because he’s the best of all time, or going towards the best of all time.”So of course to beat him you need to rise above everything you have. It’s the only way to win.”And at the end of the weekend, there is no switching off and forgetting either.”That is the tough thing about F1. It affects your wife, your mum and dad. It is not like you go home and it is all done,” said Rosberg, happy to have closed that chapter in his life.”It affects everybody. That is why it is so intense. The suffering and the joy goes all the way to your home. That never stops.”MOTIVATIONHamilton is heading for a sixth championship, one short of Schumacher’s career tally, and has 79 career wins compared to the Ferrari great’s 91.The Briton already holds the record for pole positions and has won more than half the races since the V6s were introduced in 2014.Compatriot Jenson Button, the 2009 champion, told reporters he could see Hamilton winning 10 titles before he was done but Rosberg said that would depend on the 34-year-old’s other interests.”Equalling Schumacher’s record has to be a motivation. He has this historic chance and he realistically knows he can do it. He has the car, he has the team and the regulations are not changing before 2021,” said the German.”He can equal him next year, in terms of championships, and beat him on race wins and become the best of all time. That has to be hugely motivating. It has to be. It is such an opportunity.”Rosberg, at Silverstone to promote a behavioural science programme with beer brand Heineken’s ‘When You Drive, Never Drink’ campaign, said Bottas had come back strongly from a poor 2018 season but could not afford to let the momentum slip.”He’s been struggling as of late, a little bit back to the Valtteri of last year lately, so he always needs to be careful,” he said.”If there’s too many of these last year Valtteris, then you’re going to be out.”And Lewis just gets more and more confidence and then he’s off and away again. He needs to try to keep fighting and not allow Lewis to get that self confidence.”Rosberg said the real Hamilton rarely turned up in practice — “Lewis just can’t really be bothered on Fridays” — but Saturday and Sunday was another story.”I always used to work so hard on Friday, and do the setup of the car, and then this guy comes and finally commits himself and with his natural talent, very often also taking all the setup work that I’ve done, and just out-qualifying me. “It’s horrible.” (Reporting by Alan Baldwin, editing by Toby Davis) Related News SILVERSTONE, England (Reuters) – Nico Rosberg can see Lewis Hamilton smashing Michael Schumacher’s records to become Formula One’s most successful driver, and the Briton’s former Mercedes team mate says he feels pretty good about it.The German is the only man to beat Hamilton over a season in the V6 turbo hybrid era that started in 2014 and the more success Hamilton has, the more lustre it adds to his own achievement.”It is definitely not a bad thing when I see him (Hamilton) going on to become the best of all-time and beating Schumacher’s records,” the 2016 champion told Reuters at the British Grand Prix on Saturday.”It makes me think “OK, Nico, you have done quite a good job.”center_img {{category}} {{time}} {{title}}last_img read more

Gehlot no longer has a Pilot Infighting intensifies within Rajasthan Congress

first_img Dev Ankur Wadhawan JaipurJuly 11, 2019UPDATED: July 11, 2019 20:00 IST Ashok Gehlot said that Congress chief Rahul Gandhi, who has resigned from his post, had showed faith in him for the chief minister post. (Photo: PTI)HIGHLIGHTSWith the conclusion of the Lok Sabha election 2019, infighting in Rajasthan Congress has intensifiedThe tussle between Chief Minister Ashok Gehlot and Deputy Chief Minister Sachin Pilot has come out in the openAshok Gehlot claimed that the people of Rajasthan wanted him and no one else to become the chief ministerWith the conclusion of the Lok Sabha election 2019, infighting in the upper echelons of the Congress party in Rajasthan has intensified. The tussle between Chief Minister Ashok Gehlot and Deputy Chief Minister Sachin Pilot has come out in the open in the desert state.On Wednesday, after Ashok Gehlot presented his first Budget during the state government’s present tenure, he made it obvious that he was unwilling to let go of the chief minister post.Ashok Gehlot, after presenting the state Budget in Rajasthan Assembly, had come for the customary press conference. Without even being asked about it, Ashok Gehlot claimed that the people of Rajasthan wanted him and no one else to become the chief minister.Gehlot also said that Congress chief Rahul Gandhi, who has resigned from his post, had showed faith in him for the chief minister post, further respecting the people’s sentiments.Ashok Gehlot’s statement is significant at a time when rumours of his name being under consideration for the post of Congress national president after Rahul Gandhi’s resignation.”The manner in which people chose us, I realise that there was a feeling in the last election that Ashok Gehlot should become the chief minister. The one who should become the CM and the one who should not was mentioned by name. And Rahul Gandhi, respecting the people of Rajasthan, being the Congress president, gave me this opportunity. It is my responsibility,” Rajasthan Chief Minister Ashok Gehlot said.The political tussle between Ashok Gehlot and Sachin Pilot has been no secret in the desert state. After the Assembly results were out, both the camps of Pilot and Gehlot had tried hard to ensure that their leader became the next chief minister.”Even when I was the chief minister (earlier), with this kind of love, affection, and trust, I would not have heard that which heard this time. That is why, it was appropriate for me to take the oath as the chief minister. I took it,” Gehlot added.After the Assembly results were out in December last year, accusations of internal sabotage flew thick and fast as several claimed that Ashok Gehlot’s confidantes and long time loyalists were asked to fight as Independents so that he can use them as bargaining chips if the Congress needed outside support to form the government.Some of these Independents included the likes of Mahadev Singh Khandela, MLA from Khandela, Sriganganagar MLA Raj Kumar Gaur and Babulal Nagar, MLA from Dudu.Some Independent MLAs, who were considered pro-Gehlot, later joined the Congress after Gehlot became the chief minister.Also Read | DGP given freehand to fix law and order situation in Rajasthan, says CM Ashok GehlotAlso Read | Amid leadership crisis in Congress, Ashok Gehlot meets Sonia GandhiAlso Watch | Congress CMs offer to resign from party amid dilemma over Rahul Gandhi quittingFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byShifa Naseer Tags :Follow Ashok GehlotFollow Sachin PilotFollow congress Next Gehlot no longer has a Pilot? Infighting intensifies within Rajasthan CongressOn Wednesday, after Ashok Gehlot presented his first Budget during the state government’s present tenure, he made it obvious that he was unwilling to let go of the chief minister post.advertisementlast_img read more